Advanced Breast Cancer
Advanced Breast Cancer is a stage of breast cancer where the disease has spread beyond the breast to other organs, making it more challenging to treat. Patients may experience various symptoms as the cancer progresses.
Breast Cancer: Vepdegestrant and Samuraciclib Study
We are investigating the safety and effectiveness of a new oral medication combined with another treatment for adults with advanced or metastatic hormone receptor-positive breast cancer. This study aims to find better treatment options for patients facing this condition.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you currently being treated for advanced or metastatic breast cancer?
- Have you had any other cancers in the past three years, except for certain skin cancers or cervical cancer?
- Do you have any active bleeding or serious blood disorders?
- Do you have any newly diagnosed brain metastases?
- Are you experiencing severe nausea or vomiting that prevents you from taking medications?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Ct7001
Samuraciclib
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Institut Jules Bordet
Negenmanneke, Belgium
Antwerp University Hospital
Oncology
Wilrijk, Belgium
Institut Regional Du Cancer De Montpellier
Oncologie Médicale
Grabels, France
Sponsor: Pfizer Inc.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.