Brigatinib for Pediatric and Young Adult ALK+ Cancer

We are studying the safety and effectiveness of brigatinib in children and young adults with ALK+ Anaplastic Large Cell Lymphoma and other solid tumors. This trial aims to find the best dose and understand how the drug works in these patients.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Alunbrig
Alunbrig is a cancer medicine used to treat certain types of non-small cell lung cancer with a specific genetic change.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Brigatinib
Brigatinib is a substance that blocks abnormal ALK gene activity to treat certain non-small cell lung cancers.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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St. Anna Kinderspital GmbH
Department of Pediatric Hematology and Oncology
Vienna, Austria
Universitair Ziekenhuis Gent
Pediatric Hemato-Oncology & Stem Cell Transplantation
Ledeberg, Belgium
Fakultni Nemocnice V Motole
Klinika detske hematologie a onkologie 2. LF UK
Stodůlky, Czechia

Sponsor: Prinses Maxima Centrum voor Kinderoncologie B.V.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.