Bronchiectasis: Long-Term Study of BI 1291583

We are testing the long-term safety of BI 1291583 in people with bronchiectasis who have taken part in earlier studies. The study will also look at whether this treatment helps reduce lung flare-ups.

>2 years 6-10 visits Efficacy phase (II)Post-Trial Drug Access Cost Reimbursement Partially Remote Investigational Medicines Oral InjectionPulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Icomb 2,5 Mg/2,5 Mg

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amlodipine Besilate

Amlodipine besilate is a substance that lowers high blood pressure and relaxes blood vessels to help relieve chest pain.

Ramipril

Ramipril is a substance that helps lower high blood pressure and protect the heart by relaxing blood vessels.

Salbutamol Sulfate

Salbutamol sulfate is a substance that relaxes airway muscles to quickly open breathing passages for people with asthma or COPD.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Bi 1291583

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acapril

Acovil

Alamut

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven

Pneumology

Heverlee, Belgium

Universitair Ziekenhuis Gent

Pneumologie

Ledeberg, Belgium

Medical Center Zdrave-1 OOD

Pulmology Office

Kozloduy, Bulgaria

Sponsor: Boehringer Ingelheim International GmbH

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.