C3 Glomerulopathy: Aliskiren vs. Enalapril

We are studying whether the medication aliskiren can improve kidney function in people with C3 glomerulopathy compared to the standard treatment, enalapril. This trial aims to assess its safety and effectiveness in reducing kidney disease markers.

>2 years11-15 visitsEfficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesOralInfectious DiseasesNephrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Enalapril Viatris
Enalapril Viatris is a medicine used to lower high blood pressure and help treat heart failure.
Rasilez
Rasilez is a medicine used to lower high blood pressure.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Aliskiren
Aliskiren is a substance that helps lower high blood pressure by blocking a hormone system that tightens blood vessels.
Enalapril Maleate
Enalapril maleate is a substance that lowers high blood pressure and helps the heart work better in people with heart failure.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acetensil
Analept
Aqumeldi

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Danderyds Sjukhus AB
Nephrology
Bergshamra, Sweden
Sahlgrenska University Hospital-Vaestra Goetalandsregionen
Nephrology
Göteborg, Sweden
Karolinska University Hospital
Nephrology
Huddinge, Sweden
Sponsor: Region Skane
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.