Cancer Treatment: Imipramine for Fascin1 Overexpression

We are studying whether Imipramine can change tumor characteristics in patients with cancer that over-express a protein called Fascin1. This research may help us understand its effects on tumor behavior and markers.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Tofranil
Tofranil is a medicine used to treat depression and certain anxiety disorders, and it can also help reduce bedwetting in children.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Clomipramine Hydrochloride
Clomipramine hydrochloride is a substance that helps relieve obsessive-compulsive symptoms and depression by balancing certain brain chemicals.
Imipramine Hydrochloride
Imipramine hydrochloride is a substance used to treat depression and certain anxiety disorders and to help reduce bed-wetting in children.
Sucrose
Sucrose is a common sugar used as a sweetener and a quick source of energy.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Imipramin
Imipramin Neuraxpharm
Imipramine Crescent Pharma

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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University Clinical Hospital Virgen De La Arrixaca
Medical oncology service
Fuente-Álamo de Murcia, Spain
General University Hospital Santa Lucia
Pathological anatomy service.
San Antonio Abad, Spain
Hospital General Universitario Morales Meseguer
Medical oncology service.
Velez Rubio, Spain
Sponsor: Fundacion Para La Formacion E Investigacion Sanitaria De La Region De Murcia
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.