Cancer Treatment: Long-term Study of Pembrolizumab

We are evaluating the long-term safety and survival of patients currently on pembrolizumab treatment. This study aims to understand how well the treatment works and its effects over time.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Keytruda
Keytruda is a cancer medicine that helps the immune system find and fight tumor cells.
Lenvima
Lenvima is a cancer medicine used to treat certain types of thyroid, liver, and kidney cancers.
Olapine
Olapine is a medicine used to treat schizophrenia and bipolar disorder, helping control symptoms like hallucinations, delusions, and extreme mood changes.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Lenvatinib
Lenvatinib is a substance that helps treat certain types of cancer by blocking signals tumors use to grow and spread.
Olanzapine
Olanzapine is a substance used to treat schizophrenia and bipolar disorder by helping reduce psychotic symptoms and stabilize mood.
Olaparib
Olaparib is a substance used to treat certain cancers by blocking a DNA-repair protein so cancer cells cannot fix damage and die.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Favezelimab
Mk-4280A

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aedon
Anzorin
Arenbil

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz
Universitätsklinik für Dermatologie und Venerologie
Graz, Austria
Medizinische Universitaet Innsbruck
Univ. Klinik für Dermatologie und Venerologie
Innsbruck, Austria
Krankenhaus Nord-Klinik Floridsdorf
Abteilung für Innere Medizin und Pneumologie
Langenzersdorf, Austria

Sponsor: Merck Sharp & Dohme LLC
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.