Carcinoma of Unknown Primary
Carcinoma of Unknown Primary (CUP) is a type of cancer where the primary site of the tumor cannot be identified, even after extensive testing. It often presents with metastases in various parts of the body.
Carcinoma of Unknown Primary: [18F]F-FAPI PET-CT Study
We are investigating whether [18F]F-FAPI PET-CT can help identify the primary tumor in patients with carcinoma of unknown primary. This study aims to improve diagnosis and treatment options for these patients.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years old or older?
- Do you have a known primary tumor from which your cancer has spread?
- Are you currently pregnant or breastfeeding?
- Do you have any major health issues that would prevent you from lying still for a PET-CT scan?
- Have you had any cancer treatment in the last 5 years, except for the cancer being studied?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
AlF-FAPI-74
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
Medical Oncology
Amstelveen, Netherlands
Universitair Medisch Centrum Utrecht
Radiology & Nuclear Medicine
De Bilt, Netherlands
Universitair Medisch Centrum Groningen
Medical Oncology
Groningen, Netherlands
Sponsor: Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.