Cardiogenic Shock: Levosimendan vs. Placebo

We are studying whether early use of levosimendan can improve health outcomes in patients with cardiogenic shock compared to a placebo. The goal is to see if it reduces the need for life support and improves survival rates.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Cernevit
Cernevit is a multivitamin product given through a vein to provide essential vitamins to people who cannot take them by mouth.
Dexpanthenol
Dexpanthenol is a topical medicine used to help heal, soothe, and moisturize dry or damaged skin and minor wounds.
Soluvit
Soluvit is a multivitamin solution given through a vein with IV nutrition to supply essential vitamins for people who cannot eat.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Alpha-Tocopherol
Alpha-tocopherol is known as vitamin E and acts as an antioxidant to protect cells and support skin and immune health.
Ascorbic Acid
Ascorbic acid is a substance that helps prevent vitamin C deficiency and supports immune function, collagen production, and iron absorption.
Biotin
Biotin is a B vitamin that helps the body convert food into energy and supports healthy hair, skin, and nails.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Zimino

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

3be
3be
Abidec Multivitamin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier D Avignon
Cardiologie
Avignon, France
University Hospital Of Clermont-Ferrand
cardiologie et médecine vasculaire
Beaumont, France
Hospices Civils De Lyon
Plateau urgence et soins critiques cardiologiques
Bron, France

Sponsor: CHRU De Nancy
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.