Cemiplimab and Imiquimod for High-Risk Basal Cell Carcinoma

We are studying a combination of cemiplimab, imiquimod, and laser therapy for patients with high-risk cutaneous basal cell carcinoma. The goal is to evaluate safety and how well this treatment works before surgery.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Imunocare
Libtayo
Libtayo is a cancer medicine that helps the immune system find and fight certain advanced skin and lung cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cemiplimab
Cemiplimab is a substance that helps the immune system find and attack certain cancers by blocking a protein that suppresses immune cells.
Imiquimod
Imiquimod is a substance that boosts the skin's immune response to treat certain skin growths, such as pre-cancerous patches and warts.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aksunim
Aldara
Bascellex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital Universitari Dexeus Grupo Quironsalud
Oncology
Amorebieta, Spain
Hospital Universitario Ramon Y Cajal
Oncology
Colmenar Viejo, Spain
Hospital Clinic De Barcelona
dermatology
El Altet, Spain

Sponsor: Instituto Oncologico Dr. Rosell S.L.
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.