Central Retinal Artery Occlusion: Tenecteplase Study

We are investigating whether tenecteplase can help improve vision in patients with central retinal artery occlusion when given shortly after symptoms begin. This study compares it to standard treatment to see which is more effective.

>2 years≤5 visitsConfirmation phase (III)Standard MedicinesOralInjectionCardiologyNeurologyOphthalmology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Albyl-E
Albyl-E is a low-dose aspirin medicine used to help prevent blood clots and lower the risk of heart attack and stroke.
Sodium Chloride Fresenius Kabi Italia
Sodium Chloride Fresenius Kabi Italia is a sterile saline solution used to replace fluids and salts, hydrate, and help give medicines through a vein.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Acetylsalicylic Acid
Acetylsalicylic acid is a substance that reduces pain, fever, and inflammation and can help prevent blood clots.
Sodium Chloride
Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.
Tenecteplase
Tenecteplase is a clot-dissolving substance used to quickly break up dangerous blood clots and restore blood flow in heart attacks.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Aas
Abrea
Acard

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Leuven
neurology
Heverlee, Belgium
Aarhus Universitet
Neurology
Århus, Denmark
Rigshospitalet
Neurology
Copenhagen, Denmark
Sponsor: Oslo University Hospital HF
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.