Cervical Cancer: Volrustomig Treatment Study

We are studying whether volrustomig is safe and effective for women and young adults with high-risk locally advanced cervical cancer after initial treatment. This trial compares volrustomig to a placebo to see if it improves health outcomes.

Confirmation phase (III)Post-Trial Drug AccessPartially RemoteStandard MedicinesOralInjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Mycofit
Remsima
Remsima is a medicine used to treat inflammatory immune system diseases like rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and psoriasis.
Saline
Saline is a sterile saltwater solution used to hydrate patients, replace lost fluids, and rinse wounds or medical equipment.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Hydroxyethyl Starch 130/0.4
Hydroxyethyl starch 130/0.4 is a synthetic blood volume expander given through a vein to restore blood volume and support circulation during surgery or bleeding.
Infliximab
Infliximab is a substance that reduces inflammation by blocking a protein called TNF and is used for autoimmune conditions like rheumatoid arthritis and Crohn's.
Mycophenolate Mofetil
Mycophenolate mofetil is a substance that suppresses the immune system to prevent organ transplant rejection and treat autoimmune conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens
Acuolens
Addex Natriumklorid

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Region Midtjylland
Department of Oncology
Århus, Denmark
Rigshospitalet
Department of Oncology
Copenhagen, Denmark
Odense University Hospital
Department of Oncology
Odense, Denmark
Sponsor: AstraZeneca AB
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.