Heart Failure with Reduced Ejection Fraction
Heart failure with reduced ejection fraction (HFrEF) is a condition where the heart cannot pump blood effectively, leading to symptoms such as shortness of breath, fatigue, and fluid retention.
Chronic Heart Failure: Omecamtiv Mecarbil Study
We are testing a new medication for people with chronic heart failure and severely reduced heart function. The study aims to see if it can improve heart health outcomes compared to a placebo.
>2 years11-15 visitsConfirmation phase (III)Cost ReimbursementPartially RemoteInvestigational MedicinesOralCardiologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 85 years old?
- Do you have a history of chronic heart failure requiring treatment for at least 3 months?
- Are you currently taking oral loop diuretics for your heart condition?
- Are you pregnant or planning to become pregnant during the study period?
- Have you had any major heart surgery or event in the last 3 months?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Omecamtiv Mecarbil
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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L'Hopital Prive Du Confluent
Interventional Cardiology and Care Unit
Guilers, France
Assistance Publique Hopitaux De Paris
Cardiology
Issy-les-Moulineaux, France
Centre Hospitalier Universitaire Grenoble Alpes
Cardiology
La Tronche, France
Sponsor: Cytokinetics Inc.
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.