Chronic Low Back Pain: Melatonin Study

We are investigating whether melatonin can help reduce pain in patients with chronic low back pain. Participants will compare its effects to a placebo over six weeks.

6-12 months 6-10 visits Confirmation phase (III)Cost Reimbursement Standard Medicines OralInternal MedicineOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Melatonine Tiofarma

Melatonine Tiofarma is a sleep aid that helps people fall asleep and eases short-term sleep problems like jet lag.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Lactose Monohydrate

Lactose monohydrate is a sugar substance commonly used as a filler and binder to form tablets and capsules.

Melatonin

Melatonin is a substance that helps regulate the body's sleep-wake cycle and can promote sleep or ease jet lag.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adaflex

Aritonin

Bio-Melatonin Pharmyn

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

General practice

Rotterdam, Netherlands

Sponsor: Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.