Chronic Lymphocytic Leukemia: Zanubrutinib and Obinutuzumab Study

We are studying a combination of zanubrutinib and obinutuzumab for patients with untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma. The trial aims to see if this treatment helps achieve better remission rates compared to different schedules of drug administration.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Gazyvaro
Gazyvaro is a cancer medicine used to treat certain blood cancers, including some types of lymphoma and chronic lymphocytic leukemia.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Obinutuzumab
Obinutuzumab is a lab-made antibody that targets and helps eliminate B cells to treat certain blood cancers like chronic lymphocytic and follicular lymphoma.
Zanubrutinib
Zanubrutinib is a substance that treats certain B‑cell blood cancers by blocking a protein that helps cancerous B cells grow.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Hospital Germans Trias I Pujol
Servicio de Hematología
Badalona, Spain
Hospital De La Santa Creu I Sant Pau
Servicio de Hematología
Barbastro, Spain
Hospital Del Mar
Servicio de Hematología
Barcelona, Spain

Sponsor: Pethema Fundacion
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.