Chronic Migraine: Eptinezumab for Teens

We are studying whether eptinezumab can help reduce the number of migraine days in adolescents aged 12 to 17 with chronic migraine. This trial compares the medication to a placebo to assess its effectiveness.

3-6 months ≤5 visits Confirmation phase (III)Post-Trial Drug Access Cost Reimbursement Partially Remote Standard Medicines InjectionNeurologyPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Nacl 0,9 %

A 0.9% saline solution used to hydrate people, replace lost fluids, and dilute or give medicines through a vein.

Vyepti

Vyepti is a medicine used to prevent migraine headaches in adults.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Eptinezumab

Eptinezumab is a substance that helps prevent migraine attacks by blocking a protein involved in migraine pain signaling.

Sodium Chloride

Sodium chloride is a substance used to replace salts and fluids in the body and to clean or irrigate wounds and nasal passages.

Sodium Chloride Solution 0.9%

Sodium chloride 0.9% is a sterile salt solution used to replace fluids and electrolytes, hydrate patients, and clean wounds or body cavities.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acuolens

Addex Natriumklorid

Aminoplasmal E

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azienda Socio Sanitaria Locale N. 8 Di Cagliari

Neurologist

Cagliari, Italy

Azienda Ospedaliera Universitaria Meyer IRCCS

Neurologist

Florence, Italy

IRCCS Istituto Giannina Gaslini

Neurologist

Genoa, Italy

Sponsor: H. Lundbeck A/S

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.