Chronic Pain After Mastectomy: Comparing Treatments

We are studying the effectiveness of Serratus Plane Block, capsaicin, and botulinum toxin type A for managing chronic neuropathic pain after mastectomy. This trial aims to find out which treatment offers better pain relief for those not helped by standard therapies.

>2 yearsEfficacy phase (II)No PlaceboPartially RemoteStandard MedicinesOralInjectionInternal MedicineNeurologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Midazolam
Midazolam is a medicine used to calm and sedate people for medical procedures and to help control serious seizures.
Nefopam
Nefopam is a medicine used to relieve moderate pain, often after surgery or injury.
Oxycodone
Oxycodone is a strong pain-relief medicine used to treat moderate to severe pain.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Botulinum Toxin Type A
Botulinum toxin type A is a substance that temporarily relaxes muscles to reduce wrinkles and treat muscle overactivity.
Buclizine Hydrochloride
Buclizine hydrochloride is an antihistamine substance used to prevent nausea, vomiting, and motion sickness.
Capsaicin
Capsaicin is a substance used topically to relieve nerve-related pain by reducing local nerve sensitivity.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

4-In-One Flu Relief
6 Years Plus Paracetamol Boots
Abacat

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Oscar Lambret
Department of Anesthesia, Intensive Care, and Pain Management
Loos, France
Sponsor: Centre Oscar Lambret
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.