Chronic Spontaneous Urticaria: Remibrutinib for Teens

We are studying a new medication, remibrutinib, for adolescents with chronic spontaneous urticaria that isn't well controlled by antihistamines. The goal is to see if it can reduce symptoms like hives and itching more effectively than a placebo.

3-6 months Confirmation phase (III)Post-Trial Drug Access Investigational Medicines OralAllergologyDermatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Movicol Plain

Movicol Plain is a medicine used to relieve constipation by softening stools and making bowel movements easier.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Hydrocortisone

Hydrocortisone is a substance that reduces inflammation and calms overactive immune responses for conditions like rashes, allergies, and eczema.

Macrogol 3350

Macrogol 3350 is a substance that helps soften stools and relieve constipation by drawing water into the bowel.

Potassium Chloride

Potassium chloride is a substance used to restore low potassium levels in the body and support normal heart and muscle function.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Lou064

Remibrutinib

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Accusol 35

Accusol 35 Kalium

Accusol 35 Potassium

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Goethe University Frankfurt

2004: Universitaetsklinikum Frankfurt, Klinik fuer Dermatologie, Venerologie und Allergologie

Frankfurt am Main, Germany

Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR

2000: Hautklinik und Poliklinik

Mainz, Germany

Westfaelische Wilhelms-Universitaet Muenster

2002: Klinik fuer Hautkrankheiten

Münster, Germany

Sponsor: Novartis Pharma AG

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.