Hepatic Cancer
Hepatic cancer, or liver cancer, is a type of cancer that begins in the liver cells. It can cause symptoms like weight loss, loss of appetite, and abdominal pain.
Cobolimab and Dostarlimab for Pediatric Tumors
We are studying a combination of two medications for children and young adults with newly diagnosed or relapsed solid tumors. The goal is to evaluate safety and how well it may work against specific cancers.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Rhabdomyosarcoma
Rhabdomyosarcoma is a rare type of cancer that develops in soft tissues, often affecting children. Symptoms may include swelling or a noticeable mass.
Glioma
Glioma is a type of tumor that occurs in the brain and spinal cord, arising from glial cells. Symptoms can include headaches, seizures, and changes in vision.
Malignant Melanoma
Malignant melanoma is a serious form of skin cancer that develops from melanocytes. It can appear as a new or changing mole and may spread to other parts of the body.
Melanoma Recurrent
Recurrent melanoma refers to melanoma that has returned after treatment. Symptoms may be similar to the original melanoma, including changes in the skin.
Osteosarcoma
Osteosarcoma is a type of bone cancer that typically occurs in the long bones of the arms and legs. Symptoms can include pain and swelling in the affected area.
Classical Hodgkin Lymphoma
Classical Hodgkin lymphoma is a type of cancer that affects the lymphatic system. Symptoms may include swollen lymph nodes, fever, and night sweats.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 0 and 21 years old?
- Do you have advanced or metastatic solid tumors that have not responded to previous treatments?
- Are you pregnant or breastfeeding?
- Are you currently taking steroids like Prednisone or Dexamethasone?
- Have you had major surgery in the past 28 days?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Jemperli
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Fakultni Nemocnice Brno
Klinika dětské onkologie/Department of Paediatric Oncology
Brno, Czechia
Fakultni Nemocnice V Motole
Klinika dětské hematologie a onkologie/Department of Paediatric Haematology and Oncology
Stodůlky, Czechia
Rigshospitalet
Clinical Trials Unit for Children and Adolescents with Cancer
Copenhagen, Denmark
Sponsor: Glaxosmithkline Research & Development Limited
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.