Colon Cancer: Chemotherapy Study for Older Adults

We are comparing two chemotherapy strategies for patients aged 70 and older who have had surgery for stage III colon cancer. The goal is to see which treatment helps prevent cancer from returning.

>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesOralInjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Elvorine
Folinic Acid (As Calcium Folinate) Fresenius Kabi Deutschland
Folinic Acid from Fresenius Kabi is used to protect healthy cells during certain cancer treatments and to treat or prevent low folate levels.
Xeloda
Xeloda is an oral chemotherapy medicine used to treat certain cancers, including colorectal and breast cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Calcium Folinate
Calcium folinate is a form of folate used to treat folate deficiency and reduce harmful effects of some chemotherapy.
Calcium Levofolinate
Calcium levofolinate is a substance that helps protect healthy cells during some cancer treatments and restores folate levels.
Capecitabine
Capecitabine is a substance that helps stop certain cancers from growing, commonly used for breast and colorectal cancer.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Fluorouracil

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bendafolin
Calcium Folinate As Kalceks
Calcium Folinate Fresenius Kabi

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Cliniques Saint Luc
oncology
Sint-Stevens-Woluwe, Belgium
Hôpital Avicenne
HGE
Vincennes, France
Sponsor: Fondation Franc.Cancerologie Digestive
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.