Colon Cancer: Dostarlimab with CAPEOX

We are studying a new treatment combining dostarlimab with CAPEOX for people with untreated Stage III colon cancer. The goal is to see if this combination is more effective and safe compared to CAPEOX alone.

Efficacy phase (II)No Placebo Cost Reimbursement Investigational Medicines Oral InjectionGastroenterologyOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Capecitabin Zentiva

Capecitabin Zentiva is an oral chemotherapy medicine used to treat certain cancers, such as breast and colorectal cancer.

Capecitabina Zentiva

Capecitabina Zentiva is a chemotherapy medicine used to treat certain types of cancer.

Capecitabine Accord

Capecitabine Accord is an oral cancer medicine used to treat certain types of breast and colorectal cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Capecitabine

Capecitabine is a substance that helps stop certain cancers from growing, commonly used for breast and colorectal cancer.

Dostarlimab

Dostarlimab is a monoclonal antibody that helps the immune system attack certain cancers by blocking a protein that restrains immune response.

Oxaliplatin

Oxaliplatin is a substance used in chemotherapy to treat colorectal and other cancers by killing cancer cells.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Jemperli

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Capecel

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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AZORG

Oncology

Aalst, Belgium

Az Maria Middelares Gent

Oncology

Gent, Belgium

Imelda

Oncology

Hever, Belgium

Sponsor: Glaxosmithkline Research & Development Limited

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.