Colonoscopy Prep: Mannitol vs. Plenvu®

We are studying whether mannitol is as effective and acceptable as Plenvu® for bowel preparation before a colonoscopy. This trial aims to ensure patient comfort and safety during the procedure.

3-6 months ≤5 visits Confirmation phase (III)No Placebo Partially Remote Standard Medicines OralGastroenterology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Macrogol

Macrogol is a medicine used to relieve constipation by softening stools and making bowel movements easier.

Mannitol

Mannitol is a hospital medicine used to lower high pressure in the brain or eyes and to help remove excess fluid from the body.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Macrogol

Macrogol is a substance that helps relieve constipation by softening stools and making bowel movements easier.

Macrogol 3350

Macrogol 3350 is a substance that helps soften stools and relieve constipation by drawing water into the bowel.

Macrogol 4000

Macrogol 4000 is a substance that softens stool and relieves constipation by drawing water into the bowel.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Accusol 35

Accusol 35 Kalium

Accusol 35 Potassium

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Katholieke Universiteit te Leuven

Gastroenterology department

Heverlee, Belgium

Hopital Erasme

Gastroenterology

Negenmanneke, Belgium

Algemeen Ziekenhuis Damiaan Oostende

Gastroenterology and hepatology department

Ostend, Belgium

Sponsor: Ntc S.r.l.

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.