Colorectal Cancer: Amivantamab with Chemotherapy

We are comparing a new treatment combining Amivantamab and chemotherapy to Cetuximab with chemotherapy for patients with certain types of colorectal cancer. This study aims to find out which option may help patients live longer without their cancer worsening.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Erbitux
Erbitux is a cancer treatment used to help slow the growth of certain colorectal and head and neck cancers.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amivantamab
Amivantamab is a substance that targets specific proteins on certain lung cancer cells to help control advanced non-small-cell lung cancer with EGFR exon 20 mutations.
Cetuximab
Cetuximab is a substance that targets a protein on cancer cells to help slow or stop growth in colorectal and head and neck cancers.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Jnj-61186372

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
CHU Helora
Medical oncology
Fayt-lez-Manage, Belgium
Az Maria Middelares Gent
Gastro-enterology
Gent, Belgium
UZ Leuven
Gastro-enterology
Heverlee, Belgium

Sponsor: Janssen Cilag International
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.