Colorectal Cancer: PIPAC Treatment Study

We are testing a new chemotherapy method to prevent cancer spread in patients who have had surgery for high-risk colorectal cancer. This study will help us understand its effectiveness and impact on patients' quality of life.

>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fluorouracile Ahcl
Fluorouracile Ahcl is a chemotherapy medicine used to treat various types of cancer.
Levofolene
Levofolene is a medicine used to lessen side effects of certain chemotherapy drugs and help some cancer treatments work more effectively.
Oxaliplatino Accord
Oxaliplatino Accord is a chemotherapy medicine used to treat certain cancers, commonly bowel (colorectal) cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Calcium Levofolinate
Calcium levofolinate is a substance that helps protect healthy cells during some cancer treatments and restores folate levels.
Fluorouracil
Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.
Levoleucovorin
Levoleucovorin is a form of folinic acid used to protect normal cells from toxic chemotherapy and to enhance the effect of some cancer treatments.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

5-Fluorouracil
5-Fluorouracil Ebewe
5-Fluorouracil Sandoz

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Fondazione IRCCS Istituto Nazionale Dei Tumori
Colorectal Cancer Unit
Milan, Italy
Sponsor: Fondazione IRCCS Istituto Nazionale Dei Tumori
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.