Colorectal Cancer Prevention: Mesalamine for Lynch Syndrome

We are studying whether mesalamine can help prevent colorectal cancer in patients with Lynch syndrome. This trial compares mesalamine to a placebo to see if it reduces the occurrence of tumors.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Pentasa Sachet
Pentasa Sachet is a medicine used to treat and control inflammation in the intestines, especially ulcerative colitis.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Mesalazine
Mesalazine is a substance that reduces inflammation in the bowel to help control ulcerative colitis symptoms.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Argonal
Asacol
Asacol Enema

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Aalborg University Hospital
Dept of Gastrointestinal Surgery
Aalborg, Denmark
Hvidovre Hospital
Dept of Surgical Gastroenterology, Amager Hvidovre Hospital
Hvidovre, Denmark
Region Skane Skanes Universitetssjukhus
GI-unit, 2nd floor, Jan Waldenstroems gata 14
Dalby, Sweden

Sponsor: Karolinska Institutet
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.