Colorectal Cancer: Reduced Dose Chemotherapy for Older Patients

We are studying whether a lower dose of chemotherapy is as effective as the standard dose for older patients with advanced colorectal cancer. This may help improve quality of life and reduce severe side effects.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Calcium Folinate
Calcium folinate is a form of folate used to treat folate deficiency and reduce harmful effects of some chemotherapy.
Capecitabine
Capecitabine is a substance that helps stop certain cancers from growing, commonly used for breast and colorectal cancer.
Fluorouracil
Fluorouracil is a substance used to treat cancer by stopping the growth of cancer cells.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Jeroen Bosch Ziekenhuis
Oncologie
's-Hertogenbosch, Netherlands
Noordwest Ziekenhuisgroep Stichting
Oncologie
Alkmaar, Netherlands
Ziekenhuisgroep Twente Stichting
Interne Geneeskunde
Almelo, Netherlands

Sponsor: Academisch Ziekenhuis Leiden
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.