Colorectal Cancer: Temozolomide and Irinotecan Treatment

We are studying a combination of temozolomide and irinotecan for patients with specific colorectal cancer characteristics after standard chemotherapy. The goal is to see if this treatment helps eliminate remaining cancer cells and improves survival.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Irinotecan
Irinotecan is a chemotherapy medicine used to treat certain cancers, especially colorectal cancer.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Irinotecan
Irinotecan is a chemotherapy substance used to treat certain cancers by blocking cancer cells from dividing and growing.
Irinotecan Hydrochloride
Irinotecan hydrochloride is a substance used to treat certain cancers by stopping cancer cells from growing and dividing.
Irinotecan Hydrochloride Trihydrate
Irinotecan hydrochloride trihydrate is a chemotherapy agent used to treat several types of cancer, especially colorectal cancer.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Campto
Canri
Chlorhydrate D'irinotécan Trihydraté Sun

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I G M Lancisi G Salesi
Oncologia Medica
Ancona, Italy
Centro Di Riferimento Oncologico Di Aviano
Dipartimento di oncologia medica e prevenzione oncologica
Aviano-Castello, Italy
Fondazione Poliambulanza
ONCOLOGIA MEDICA
Brescia, Italy

Sponsor: Fondazione IRCCS Istituto Nazionale Dei Tumori
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.