Coronary Artery Spasm: Testing Bosentan

We are studying whether the medication bosentan can help reduce coronary artery spasms in patients with ongoing angina symptoms. The trial also aims to evaluate its effects on quality of life and safety.

≤3 months≤5 visitsEfficacy phase (II)Confirmation phase (III)Post-Trial Drug AccessCost ReimbursementPartially RemoteInvestigational MedicinesOralCardiologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Bosentan Abdi
Bosentan Abdi is a medicine used to treat high blood pressure in the lungs.
Bosentan Accord
Bosentan Accord is a medicine used to treat high blood pressure in the lungs, a condition called pulmonary arterial hypertension.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Bosentan
Bosentan is a substance that widens lung blood vessels to lower high pulmonary blood pressure and improve breathing in pulmonary arterial hypertension.
Bosentan Monohydrate
Bosentan monohydrate is a substance that lowers high blood pressure in the lungs by blocking signals that tighten lung blood vessels.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Microcrystalline Cellulose

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Bactoced
Bocleer
Bopaho

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

Loading map...
Amsterdam UMC Stichting
Cardiology
Abcoude, Netherlands
Maasstad Ziekenhuis Stichting
Cardiology
Barendrecht, Netherlands
Universitair Medisch Centrum Utrecht
Cardiology
De Bilt, Netherlands
Sponsor: Stichting Radboud University Medical Center
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.