COVID-19 Treatment: Antiviral Therapy for Immunocompromised Patients

We are studying a combination of antiviral medications to see if it helps immunocompromised patients recover from COVID-19 more effectively. The goal is to improve viral clearance and reduce symptoms compared to standard treatments.

3-6 months ≤5 visits Efficacy phase (II)No Placebo Partially Remote Standard Medicines Oral InjectionInfectious DiseasesInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Paxlovid

Paxlovid is a prescription medicine that treats COVID-19 and lowers the risk of severe illness when taken early.

Veklury

Veklury is an antiviral medicine used to treat COVID-19 in people who are hospitalized or at risk of severe illness.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Nirmatrelvir

Nirmatrelvir is an antiviral substance that blocks a key coronavirus protein to help treat early COVID-19.

Remdesivir

Remdesivir is an antiviral substance used to treat certain severe viral infections, including COVID-19.

Ritonavir

Ritonavir is a substance that helps treat HIV by blocking a viral enzyme and boosting the effects of other HIV treatments.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Kaletra

Lopinavir / Ritonavir Accord

Lopinavir / Ritonavir Sun

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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CHU De Toulouse

Infectious diseases

Blagnac, France

CHU Bordeauxt

Internal medicine

Bordeaux, France

Pellegrin Hospital

Infectious diseases

Bordeaux, France

Sponsor: Inserm

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.