COVID-19 Treatment: Nirmatrelvir/Ritonavir for Children

We are studying a new oral medication for children with COVID-19 who are at risk of severe illness. The trial will evaluate its safety, how well it works, and how it is tolerated in young patients.

6-10 visits Efficacy phase (II)Confirmation phase (III)No Placebo Cost Reimbursement Partially Remote Standard Medicines OralInfectious DiseasesPediatrics

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Ritonavir Sandoz

Ritonavir Sandoz is a medicine used to treat HIV infection and to boost other HIV drugs.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Nirmatrelvir

Nirmatrelvir is an antiviral substance that blocks a key coronavirus protein to help treat early COVID-19.

Ritonavir

Ritonavir is a substance that helps treat HIV by blocking a viral enzyme and boosting the effects of other HIV treatments.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Kaletra

Lopinavir / Ritonavir Accord

Lopinavir / Ritonavir Sun

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Multiprofile Hospital For Active Treatment St. Ivan Rilski Gorna Oriahovitsa EOOD

Pediatric department

Gorna Oryahovitsa, Bulgaria

Specialized Hospital For Active Treatment Of Pneumo-Phthisiatric Diseases Dr. Dimitar Gramatikov-Ruse

First Department of Pneumology

Ruse, Bulgaria

Medical Center 1 Sevlievo EOOD

Sevlievo, Bulgaria

Sponsor: Pfizer Inc.

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.