Crohn's Disease: Obefazimod Study

We are testing a new medication, obefazimod, for people with moderately to severely active Crohn's disease who haven't responded to other treatments. The study aims to see if it is more effective and safe compared to a placebo.

>2 years 11-15 visits Efficacy phase (II)Post-Trial Drug Access Cost Reimbursement Investigational Medicines OralGastroenterologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Abix

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Hydrocortisone

Hydrocortisone is a substance that reduces inflammation and calms overactive immune responses for conditions like rashes, allergies, and eczema.

Placebo

Placebo is an inactive substance given to mimic a treatment so researchers can measure effects caused by patients' expectations.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Obefazimod

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acecort

Actocortina

Adhoc

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Az Maria Middelares Gent

Gastroenterology

Gent, Belgium

UZ Leuven

Gastroenterology

Heverlee, Belgium

Universitair Ziekenhuis Gent

Gastroenterology

Ledeberg, Belgium

Sponsor: Abivax

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.