Crohn's Disease
Crohn's Disease is a type of inflammatory bowel disease (IBD) that causes inflammation of the digestive tract, leading to symptoms like abdominal pain, diarrhea, and weight loss.
Crohn’s Disease and Ulcerative Colitis: Tulisokibart Study
We are studying the long-term safety and effectiveness of tulisokibart in people with Crohn’s disease or ulcerative colitis. This research aims to see how well the treatment helps manage symptoms and achieve remission.
>2 years>20 visitsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesInjectionGastroenterologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Ulcerative Colitis
Ulcerative Colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the lining of the colon, resulting in symptoms such as abdominal pain, diarrhea, and rectal bleeding.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you assigned female at birth and not breastfeeding during the study intervention period and for at least 14 weeks after the last dose?
- Are you of childbearing potential and not pregnant while using an acceptable form of contraception or abstinence?
- Have you participated in a qualifying MSD-sponsored tulisokibart Phase 2 or Phase 3 parent study for Crohn’s Disease or Ulcerative Colitis?
- Have you ever had an allergy or intolerance to tulisokibart or its ingredients?
- Are you currently participating in any other clinical study that is not a qualifying tulisokibart Phase 2 or Phase 3 parent study for Crohn’s Disease or Ulcerative Colitis?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Tulisokibart
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Vojenska Nemocnice Brno
Vojenska Nemocnice Brno
Brno, Czechia
Hepato-Gastroenterologie HK s.r.o.
Hepato-Gastroenterologie HK s.r.o.
Hradec Králové, Czechia
Centre Hospitalier Universitaire De Lille
Hépato-Gastro-Entérologie
Loos, France
Sponsor: Merck Sharp & Dohme LLC
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.