Crohn's Disease
Crohn's Disease is a type of inflammatory bowel disease (IBD) that causes inflammation of the digestive tract, leading to symptoms such as abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition.
Crohn’s Disease: Tulisokibart Treatment Study
We are testing a new medication, tulisokibart, for people with moderately to severely active Crohn’s disease. The goal is to see if it helps achieve remission and improve symptoms compared to a placebo.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 16 and 18 years old?
- Do you have Crohn’s Disease (CD) diagnosed at least 3 months ago?
- Do you have moderately to severely active Crohn’s Disease?
- Have you had any surgery related to your Crohn’s Disease in the last 3 months?
- Do you have any other inflammatory bowel disease like ulcerative colitis?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Tulisokibart
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Medizinische Universitaet Innsbruck
Universitätsklinik für Innere Medizin I
Innsbruck, Austria
Gemeinnuetzige Salzburger Landeskliniken Betriebsgesellschaft mbH
Universitätsklinik für Innere Medizin I
Salzburg, Austria
Medical University Of Vienna
Abteilung für Gastroenterologie und Hepatologie, 7I
Vienna, Austria
UZ Leuven
Maag-darm-leverziekten
Heverlee, Belgium
Universitair Ziekenhuis Gent
IBD-centrum
Ledeberg, Belgium
Algemeen Ziekenhuis Delta
Maag-darm-leverziekten
Rumbeke, Belgium
Poliklinika Borzan d.o.o.
Osijek, Croatia
Klinicka bolnica Merkur
Zagreb, Croatia
Poliklinika Bates
Zagreb, Croatia
Poliklinika Solmed d.o.o.
Zagreb, Croatia
University Hospital Centre Zagreb
Zavod za gastroenterologiju i hepatologiju
Zagreb, Croatia
Pratia Brno s.r.o.
Gastroenterologicka ambulance
Brno, Czechia
Vojenska Nemocnice Brno
Interni oddeleni
Brno, Czechia
Iscare a.s.
Gastroenterologie IBD centrum
Čakovice, Czechia
Hepato-Gastroenterologie HK s.r.o.
Hepato-Gastroenterologie
Hradec Králové, Czechia
Institute For Clinical And Experimental Medicine
Klinika hepatogastroentrologie
Prague, Czechia
Nemocnice Slany
Gastroenterologicka a hepatologicka ambulance
Slaný, Czechia
Odense University Hospital
Gastroenterologisk afdeling
Odense, Denmark
Region Hovedstaden
Afdeling for mave-, tarm- og leversygdomme
Rødovre, Denmark
North Karelia Central Hospital
Gastroenterology
Joensuu, Finland
Tampere University Hospital
Gastroenterology Outpatient Clinic
Tampere, Finland
Turku University Hospital
Gastroenterology Outpatient Clinic
Turku, Finland
CHU Besancon
Hépato-Gastro-Entérologie
Besançon, France
Centre Hospitalier Universitaire De Bordeaux
Hépato-Gastro-Entérologie
Canéjan, France
Assistance Publique Hopitaux De Paris
Hépato-Gastro-Entérologie
Clichy, France
Centre Hospitalier Universitaire Amiens Picardie
Hépato-Gastro-Entérologie
Colomiers, France
Centre Hospitalier Universitaire Reims
Hépato-Gastro-Entérologie
Cormontreuil, France
Assistance Publique Hopitaux De Paris
Hépato-Gastro-Entérologie
Créteil, France
Assistance Publique Hopitaux De Paris
Hépato-Gastro-Entérologie
Croulebarbe, France
Clinique Des Cedres.
Hépato-Gastro-Entérologie
Échirolles, France
Centre Hospitalier Universitaire De Lille
Hépato-Gastro-Entérologie
Loos, France
Centre Hospitalier Universitaire De Nimes
Hépato-Gastro-Entérologie
Milhaud, France
Centre Hospitalier Universitaire De Nantes
Hépato-Gastro-Entérologie
Nantes, France
Centre Medico Chirurgical Ambroise Pare Hartmann
Hépato-Gastro-Entérologie
Neuilly-sur-Seine, France
Centre Hospitalier Universitaire De Nice
Hépato-Gastro-Entérologie
Nice, France
Hospices Civils De Lyon
Hépato-Gastro-Entérologie
Oullins, France
Assistance Publique Hopitaux De Paris
Hépato-Gastro-Entérologie
Quinze-Vingts, France
Centre Hospitalier Universitaire De Toulouse
Hépato-Gastro-Entérologie
Ramonville-Saint-Agne, France
Centre Hospitalier Universitaire De Dijon
Hépato-Gastro-Entérologie
Saint-Apollinaire, France
Centre Hospitalier Regional De Marseille
Hépato-Gastro-Entérologie
Septèmes-les-Vallons, France
CHRU De Nancy
Hépato-Gastro-Entérologie
Vandœuvre-lès-Nancy, France
Charite Universitaetsmedizin Berlin KöR
Medizinische Klinik für Hepatologie und Gastroenterologie
Berlin, Germany
Universitaetsklinikum Brandenburg an der Havel GmbH
Klinik für Innere Medizin II
Brandenburg an der Havel, Germany
Medizinisches Versorgungszentrum fuer spezialaerztliche Versorgung Professor Dr. Friedrichs GmbH
"Medizinische Klinik II Gastroenterologie und Hepatologie
Duisburg, Germany
Universitaetsklinikum Schleswig-Holstein AöR
Klinik für Innere Medizin I
Kiel, Germany
Universitaetsklinikum Ulm AöR
Klinik für Innere Medizin I
Klingenstein, Germany
Evangelisches Krankenhaus Kalk gGmbH
Klinik für Gastroenterologie, Pulmologie, allg. Innere Medizin
Köln, Germany
Medizinische Hochschule Hannover
Klinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie
Laatzen, Germany
Universitaetsklinikum Leipzig AöR
Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie und Pneumologie
Leipzig, Germany
Staedtisches Klinikum Lueneburg gGmbH
Klinik für Allgemeine Innere Medizin, Gastroenterologie und Pneumologie
Lüneburg, Germany
Gastroenterologische Gemeinschaftspraxis Minden
Gastroenterologische Gemeinschaftspraxis Minden
Minden, Germany
Klinikum der Technischen Universitaet Muenchen (TUM Klinikum)
Klinik und Poliklinik für Innere Medizin II
Munich, Germany
Medizinisches Versorgungszentrum Portal 10
Zentrum für Leber-, Magen- und Darmerkrankungen
Münster, Germany
St. Marien Und St. Annastiftskrankenhaus
Klinik für Innere Medizin - Gastroenterologie
Neuhofen, Germany
LMU Klinikum Muenchen AöR
Medizinische Klinik und Poliklinik II
Neuried, Germany
Siloah St Trudpert Klinikum
Klinik für Innere Medizin I
Pforzheim, Germany
Magen-Darm-Zentrum Remscheid
Magen-Darm-Zentrum Remscheid
Remscheid, Germany
Rostock University Medical Center
Zentrum für Innere Medizin - Abteilung für Gastroenterologie und Endokrinologie
Rostock, Germany
Geniko Nosokomeio Nikaias Peiraia Ag. Panteleimon Geniko Nosokomeio Dytikis Attikis I
Department of Gastroenterology
Agios Ioannis Rentis, Greece
Evangelismos S.A.
Gastroenterology Department
Athens, Greece
Thoracic General Hospital Of Athens I Sotiria
GI Unit, 3rd Academic Department of Internal Medicine
Athens, Greece
University General Hospital Of Heraklion
Gastroenterology Department
Irákleion, Greece
Hippokration Hospital
2nd Propedeutic Department of Internal Medicine
Thessaloníki, Greece
Bekes Varmegyei Koezponti Korhaz
4.Belgyógyászat- 2.Gasztroenterológia
Békéscsaba, Hungary
Central Hospital Of Northern Pest Military Hospital
Gasztroenterológia
Budapest, Hungary
Clinexpert Kft.
Budapest, Hungary
Pannonia Maganorvosi Centrum Kft.
Budapest, Hungary
Semmelweis University
Sebészeti, Transzplantációs és Gasztroenterológiai Klinika
Budapest, Hungary
Heves Varmegyei Markhot Ferenc Oktatokorhaz Es Rendelointezet
Belgyógyászati-Infektológiai Centrum, Gasztroenterológiai Részleg
Eger, Hungary
Gyoengyosi Bugat Pal Koerhaz
Gasztroenterológiai Egység
Gyöngyös, Hungary
Komarom-Esztergom Varmegyei Szent Borbala Korhaz
Gasztroenterológia
Tatabánya, Hungary
VeszLife Kft.
Veszprém, Hungary
Beaumont Hospital
Gastroenterology
Beaumont, Ireland
Azienda Universitaria Ospedaliera Consorziale Policlinico Bari
U.O. Gastroenterologia
Altamura, Italy
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico
Struttura Semplice Dipartimentale per le Malattie Infiammatorie Croniche Intestinali
Bologna, Italy
Azienda Ospedaliera Policlinico Universitario Tor Vergata
U.O.C. Gastroenterologia
Ciampino, Italy
Azienda Ospedaliero Universitaria Careggi
S.O.D. Gastroenterologia
Florence, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
UOC CEMAD - UOS Malattie Infiammatorie Croniche Intestinali
La Massimina-Casal Lumbroso, Italy
Azienda Ospedaliera Universitaria Gaetano Martino Messina
UOC Gastroenterologia e Malattie Intestinali Croniche
Messina, Italy
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
Unità di Gastroenterologia ed Endoscopia
Milan, Italy
Azienda Ospedaliero-Universitaria Di Cagliari
S.C. Gastroenterologia
Monserrato, Italy
IRCCS Ospedale Sacro Cuore Don Calabria
Malattie Croniche Intestinali – IBD Unit
Negrar, Italy
Azienda Unita' Sanitaria Locale Toscana Nord Ovest
Endoscopia Digestiva
Pontedera, Italy
Humanitas Mirasole S.p.A.
Unità Operativa Malattie Infiammatorie Croniche Intestinali
Rozzano, Italy
Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello
U.O.S.D. Malattie Infiammatorie Croniche dell'Intestino (M.I.C.I.)
Sferracavallo, Italy
Azienda Ospedaliera Dei Colli
U.O.C. Gastroenterologia ed Endoscopia Digestiva
Soccavo, Italy
Azienda Ospedaliera Ordine Mauriziano Di Torino
S.C. Gastroenterologia
Turin, Italy
Ospedale San Raffaele S.r.l.
Unità Operativa di Gastroenterologia ed Endoscopia Digestiva
Vimodrone, Italy
M & M centrs SIA
Doctor practice
Ādaži, Latvia
Pauls Stradins Clinical University Hospital
Gastroenterology department
Mārupe, Latvia
Lietuvos sveikatos mokslu universiteto ligonine Kauno klinikos
Gastroenterology department
Kaunas, Lithuania
Vilniaus Universiteto Ligonine Santaros Klinikos Vsi
Department of Clinical trails and Pharmacology
Vilnius, Lithuania
Amsterdam UMC Stichting
Department of Gastroenterology & hepatology
Amstelveen, Netherlands
Universitair Medisch Centrum Utrecht
Department of Gastroenterology & hepatology
De Bilt, Netherlands
Universitair Medisch Centrum Groningen
Department of Gastroenterology & hepatology
Groningen, Netherlands
Radboud universitair medisch centrum Stichting
Department of Gastroenterology & hepatology
Nijmegen, Netherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Department of Gastroenterology & hepatology
Rotterdam, Netherlands
Sint Franciscus Vlietland Groep Stichting
Department of Gastroenterology & hepatology
Rotterdam, Netherlands
Stichting Elisabeth-Tweesteden Ziekenhuis
Department of Gastroenterology & hepatology
Tilburg, Netherlands
Bernhoven B.V.
Department of Gastroenterology & hepatology
Uden, Netherlands
Centrum Medyczne Kermed Renata Bijata-Bronisz I Ewa Kowalinska Sp. j.
NZOZ Centrum Medyczne KERmed
Bydgoszcz, Poland
M2M Med. Sp. z o.o. Sp. j.
Chorzów, Poland
Promed P.Lach R.Glowacki Sp. j.
Centrum Medyczne PROMED
Grzegórzki, Poland
Topolowa Medicenter Ryszawa & Wspolnicy Sp. j.
Grzegórzki, Poland
Amicare Sp. z o.o. S.K.
Jelenia Góra, Poland
Centrum Medyczne Plejady Magdalena Celinska Loewenhoff Michal Zolnowski sp.k.
Centrum Medyczne Plejady
Kraków, Poland
Futuremeds Sp. z o.o.
Futuremeds Kraków
Kraków, Poland
Centrum Medyczne Med-Gastr Sp. z o.o.
Łódź, Poland
Ip Clinic Sp. z o.o.
Łódź, Poland
Medrise Sp. z o.o.
Lublin, Poland
Uniwersytecki Szpital Kliniczny Nr 4 W Lublinie
Kliniczny Oddział Gastroenterologii, Hepatologii i Chorób Wewnętrznych
Lublin, Poland
Twoja Przychodnia Poznanskie Centrum Medyczne Sp. z o.o.
Twoja Przychodnia PCM
Luboń, Poland
Allmedica Badania Kliniczne Sp. z o.o. sp.k.
Nowy Targ, Poland
Etg Warszawa Sp. z o.o.
Ochota, Poland
NOVAMED ROBERT KOTERAS
Twoja Przychodnia Opolskie Centrum Medyczne
Opole, Poland
Medicome Sp. z o.o.
Oświęcimskie Centrum Badań Klinicznych
Oświęcim, Poland
EMC Instytut Medyczny S.A.
Prywatna Lecznica Certus – Szpital i Ambulatorium
Plewiska, Poland
Pratia S.A.
Pratia Poznań
Plewiska, Poland
Medical Network Sp. z o.o.
WIP Warsaw IBD Point Profesor Kierkuś
Rembertów, Poland
Endoskopia Sp. z o.o.
Sopot, Poland
Sonomed Sp. z o.o.
Szczecin, Poland
Twoja Przychodnia Szczecinskie Centrum Medyczne Sp. z o.o.
Twoja Przychodnia SCM
Szczecin, Poland
Vivamed Sp. z o.o.
Targówek, Poland
Gastromed Sp. z o.o.
Toruń, Poland
H-T.Centrum Medyczne Sp. z o.o. sp.k.
Endoterapia
Tychy, Poland
Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy
Klinika Gastroenterologii Onkologicznej
Ursynów, Poland
EMC Instytut Medyczny S.A.
EuroMediCare Przychodnia Specjalistyczna we Wrocławiu
Wrocław, Poland
Melita Medical Sp. z o.o.
Centrum Medyczne Melita Medical
Wrocław, Poland
Planetmed Sp. z o.o.
Wrocław, Poland
Vistamed & Vertigo Sp. z o.o.
VISTAMED
Wrocław, Poland
Etg Zamosc Sp. z o.o.
ETG Zamość Poradnie Specjalistyczne
Zamość, Poland
Amicare Sp. z o.o. S.K.
Zgierz, Poland
Eb Group Sp. z o.o.
Centrum Zdrowia MDM
Żoliborz, Poland
Hospital Da Luz S.A.
Serviço de Gastroenterologia
Benfica, Portugal
Lusiadas S.A.
Serviço de Gastroenterologia
Campo Grande, Portugal
Unidade Local De Saude Do Alto Ave E.P.E.
Serviço de Gastroenterologia
Guimarães, Portugal
Unidade Local De Saude Da Regiao De Leiria E.P.E.
Serviço de Gastroenterologia
Leiria, Portugal
Unidade Local de Saude do Algarve E.P.E.
Serviço de Gastroenterologia
Portimão, Portugal
Unidade Local De Saude Do Alto Minho E.P.E.
Serviço de Gastrenterologia
Viana do Castelo, Portugal
Unidade Local De Saude De Viseu Dao-Lafoes E.P.E.
Serviço de Gastrenterologia
Viseu, Portugal
Monza-Ares S.R.L.
Gastroenterology
Bucharest, Romania
Gastro Med S.R.L.
Gastroenterology
Cluj-Napoca, Romania
Memorial Healthcare International S.R.L.
Gastroenterology
Mogoşoaia, Romania
Spitalul Clinic Judetean Mures
Gastroenterology
Sângeorgiu de Mureş, Romania
Asociatia Oncohelp
Gastroenterology
Timişoara, Romania
Institutul Clinic Fundeni
Gastroenterology
Voluntari, Romania
F D Roosevelt University General Hospital Of Banska Bystrica
Gastroenterologická ambulancia
Banská Bystrica, Slovakia
Cliniq s.r.o.
Gastroenterologické centrum
Bratislava, Slovakia
KM Management spol. s r.o.
Gastroenterologické a hepatologické centrum
Nitra, Slovakia
Gastro I s.r.o.
Gastroenterologická ambulancia
Prešov, Slovakia
Gastro LM s.r.o.
Gastroenterológia
Prešov, Slovakia
Hospital Germans Trias I Pujol
Aparato Digestivo
Badalona, Spain
Hospital Universitario La Paz
Aparato Digestivo
Chamartín, Spain
Hospital Universitario Puerta De Hierro De Majadahonda
Aparato Digestivo
Chamartín, Spain
Hospital Clinic De Barcelona
Servicio de Gastroenterología
El Altet, Spain
Hospital Universitario Nuestra Senora De Candelaria
Aparato Digestivo
La Laguna, Spain
Area Sanitaria De Ferrol
Departamente de Gastroenterologia
Narón, Spain
Complexo Hospitalario Universitario De Pontevedra
Aparato Digestivo
San Fernando, Spain
Hospital Universitario Y Politecnico La Fe
Aparato Digestivo
Sedaví, Spain
Hospital Universitario De Torrejon
Aparato Digestivo
Torrejón de Ardoz, Spain
Hospital Clinico Universitario De Valencia
Aparato Digestivo
Valencia, Spain
Hospital Universitario Miguel Servet
Servicio de Gastroenterología
Zaragoza, Spain
Danderyds Sjukhus AB
Gastrosektionen VO Medicinsk Specialistvård
Bergshamra, Sweden
Region Oestergoetland
Mag-tarmmedicinska kliniken
Linköping, Sweden
Karolinska University Hospital
Tema Inflammation & Åldrande, IBD Mag-Tarm, Forskning
Solna, Sweden
Sponsor: Merck Sharp & Dohme LLC
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.