Cutibacterium acnes Infections: Rifampicin Study

We are investigating whether rifampicin is safe and effective for treating prosthetic joint infections caused by Cutibacterium acnes. This study compares rifampicin with other antibiotic treatments to see which works better.

>2 years 6-10 visits Efficacy phase (II)Confirmation phase (III)No Placebo Cost Reimbursement Partially Remote Standard Medicines OralInfectious DiseasesOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Clindamycin

Clindamycin is an antibiotic medicine used to treat various bacterial infections, including skin and respiratory infections.

Moxifloxacin

Moxifloxacin is an antibiotic used to treat various bacterial infections, including certain respiratory, sinus, and skin infections.

Rifadine

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Amoxicillin

Amoxicillin is an antibiotic substance used to treat a range of common bacterial infections such as ear, throat, and urinary tract infections.

Clindamycin

Clindamycin is an antibiotic substance used to treat various bacterial infections, including skin and respiratory infections.

Clindamycin Phosphate

Clindamycin phosphate is an antibiotic substance used to treat bacterial infections, including skin infections and acne.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abimox

Abiox

Actira

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Annecy Genevois

Infectiologie

Annecy, France

Groupe hospitalier Diaconesses Croix Saint Simon

Infectiologie

Bagnolet, France

Centre Hospitalier Universitaire De Toulouse

Infectiologie

Blagnac, France

Sponsor: Centre Hospitalier Universitaire De Nice

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.