Cytomegalovirus Treatment: Letermovir and Valganciclovir Combination

We are studying whether a combination of letermovir and valganciclovir helps kidney transplant recipients with CMV infections achieve better viral response than valganciclovir alone.

>2 years11-15 visitsConfirmation phase (III)Investigational MedicinesOralInfectious DiseasesNephrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Valganciclovir Eg
Valganciclovir Eg is a medicine used to treat and prevent CMV, a virus that can cause serious infections in people with weakened immune systems.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Letermovir
Letermovir is a substance that helps prevent cytomegalovirus (CMV) infection in people at high risk after stem cell transplantation.
Valganciclovir
Valganciclovir is an antiviral substance used to treat and prevent cytomegalovirus infections, especially in people with weakened immune systems.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Prevymis

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Alvanocyt
Ceglar
Cytevix

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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CHU De Rouen
Néphrologie, Transplantation et Hémodialyse, Hôpital de Bois Guillaume
Bois-Guillaume, France
Centre Hospitalier Universitaire De Bordeaux
Néphrologie - Transplantation – Dialyse – Aphérèses. Hôpital Pellegrin
Bordeaux, France
Assistance Publique Hopitaux De Paris
Néphrologie et transplantation
Créteil, France
Sponsor: Assistance Publique Hopitaux De Paris
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.