Dapagliflozin for Decompensated Liver Cirrhosis

We are studying whether dapagliflozin is safe and effective for patients with decompensated liver cirrhosis compared to standard treatments. The trial also looks at how it may affect quality of life and various health markers.

6-12 months 6-10 visits Efficacy phase (II)No Placebo Standard Medicines OralHepatologyInternal Medicine

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Forxiga

Forxiga is a medicine that lowers blood sugar in adults with type 2 diabetes and can also help certain heart and kidney conditions.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Dapagliflozin

Dapagliflozin is a substance that helps lower blood sugar in people with type 2 diabetes by causing the kidneys to remove excess glucose in urine.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Brolertix

Daforbis

Dagetia

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico

Dipartimento di Scienze Mediche e Chirurgiche (DIMEC)

Bologna, Italy

ASST Grande Ospedale Metropolitano Niguarda

U.O.C. Epatologia e Gastroenterologia, Dipartimento Medico Polispecialistico

Bresso, Italy

Azienda Ospedale-Universita Padova

UOC Medicina Interna a indirizzo Epatologico, Didas Medicina dei Sistemi

Padova, Italy

Sponsor: Azienda Ospedale-Universita Padova

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.