Dent 2 Disease: Alpelisib Study

We are testing the medication alpelisib in patients with Dent 2 disease to see if it improves kidney function and is safe to use. This study will help us understand its potential benefits for kidney health.

≤5 visits Efficacy phase (II)No Placebo Cost Reimbursement Standard Medicines Oral InjectionNephrologyUrology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Piqray

Piqray is a cancer medicine used with hormone therapy to treat certain advanced breast cancers.

Renocis

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Alpelisib

Alpelisib is a substance that targets a cancer growth pathway to treat certain breast cancers with specific gene mutations.

Dimercaptosuccinic Acid

Dimercaptosuccinic acid is a substance that helps bind and remove heavy metals, such as lead, from the body.

Succimer

Succimer is a substance that binds and helps remove lead from the body in people with lead poisoning.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Technescan Dmsa

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Ospedale Pediatrico Bambino Gesu

Division of Nephrology and Dialysis

Rome, Italy

Sponsor: Ospedale Pediatrico Bambino Gesu

Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.