Difelikefalin for Itching in Adolescents on Hemodialysis

We are studying whether difelikefalin is safe for adolescents aged 12 to 17 who have moderate-to-severe itching related to long-term kidney disease. This trial aims to help improve care for young patients undergoing hemodialysis.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Kapruvia

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Difelikefalin
Difelikefalin is a substance that reduces severe itching, especially in people with kidney disease receiving dialysis.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Athens General Children's Hospital Panagioti And Aglaia Kyriakou
Nephrology Department
Athens, Greece
Ippokratio General Hospital Of Thessaloniki
1st Department of Pediatrics, Aristotle University of Thessaloniki
Thessaloníki, Greece
ARNAS Civico Di Cristina Benfratelli
Pediatric Nephrology
Palermo, Italy

Sponsor: Vifor Fresenius Medical Care Renal Pharma Ltd.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.