Diffuse Cutaneous Systemic Sclerosis: Ianalumab Study

We are testing a new medication, ianalumab, for people with diffuse cutaneous systemic sclerosis. The goal is to see if it improves symptoms and lung function compared to a placebo.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Entecavir Eg
Entecavir Eg is a medicine used to treat chronic hepatitis B by helping stop the virus from multiplying.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Entecavir
Entecavir is an antiviral substance used to treat chronic hepatitis B by stopping the hepatitis B virus from multiplying.
Tenofovir Alafenamide
Tenofovir alafenamide is an antiviral substance used to treat and control HIV and chronic hepatitis B infections.
Tenofovir Disoproxil
Tenofovir disoproxil is a substance that helps stop certain viruses (including HIV and hepatitis B) from multiplying in the body.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Vay736
Ianalumab

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Baraclude
Edevira
Entecavir Accord

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical University Of Graz
3300 : Internal Medicines
Graz, Austria
UZ Leuven
2900 : Rheumatology
Heverlee, Belgium
Centre Hospitalier Le Mans
2505:Rhumatology and Immunology
Coulaines, France

Sponsor: Novartis Pharma AG
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.