Diffuse Large B-Cell Lymphoma: Epcoritamab Plus Lenalidomide

We are studying whether a new combination of epcoritamab and lenalidomide can improve survival rates for adults with relapsed or refractory diffuse large B-cell lymphoma compared to standard treatments.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Revlimid
Revlimid is a cancer medicine used to treat certain blood cancers and bone marrow disorders, including multiple myeloma.
Truxima
Truxima is a medicine used to treat certain blood cancers and some autoimmune diseases by targeting and reducing harmful immune cells.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Epcoritamab
Epcoritamab is a lab-made antibody that helps the immune system target and kill cancerous B cells in certain types of non-Hodgkin lymphoma.
Gemcitabine
Gemcitabine is a substance that slows or stops cancer cell growth and is used to treat several cancers, including pancreatic and lung.
Lenalidomide
Lenalidomide is a substance that helps treat certain blood cancers by affecting the immune system to stop cancer growth.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

7,5 Mg Stada
Blitzima
Cortedal

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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UZ Brussel
Hematology
Ganshoren, Belgium
UZ Leuven
Hematology
Heverlee, Belgium
Centre Hospitalier EPICURA
Hematology
Hornu, Belgium

Sponsor: AbbVie Deutschland GmbH & Co. KG
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.