Diffuse Large B-Cell Lymphoma (DLBCL)
Diffuse Large B-Cell Lymphoma (DLBCL) is a fast-growing type of non-Hodgkin lymphoma that affects B-cells, leading to symptoms like swollen lymph nodes, fever, and weight loss.
Diffuse Large B-cell Lymphoma: Loncastuximab and Epcoritamab Study
We are studying a combination of two medications for patients with relapsed or refractory diffuse large B-cell lymphoma. The goal is to see how well this treatment works and its safety compared to existing options.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Follicular Lymphoma (FL) Grade 3B
Follicular Lymphoma (FL) Grade 3B is a type of non-Hodgkin lymphoma that is generally slow-growing but can transform into a more aggressive form, causing symptoms like swollen lymph nodes and fatigue.
High-Grade B-Cell Lymphoma (HGBL)
High-Grade B-Cell Lymphoma (HGBL) is a rapidly progressing form of lymphoma that affects B-cells, often presenting with symptoms such as swollen lymph nodes, fever, and significant weight loss.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you 18 years or older?
- Do you have relapsed or refractory DLBCL (a type of blood cancer)?
- Are you currently pregnant or breastfeeding?
- Are you taking any medications that lower your immune system, like steroids (e.g., Prednisone) or other immunosuppressants?
- Have you had any major surgery in the past 4 weeks?
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Vivantes Netzwerk fuer Gesundheit GmbH
Hematology, Oncology and palliative care
Berlin, Germany
HELIOS Klinikum Berlin-Buch GmbH
Clinic for Hematology and Stem Cell Transplantation
Bernau bei Berlin, Germany
Evangelisches Klinikum Bethel gGmbH
Dept. of Hematology/Medical Oncology
Bielefeld, Germany
Sponsor: Universitaet Muenster
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.