Dilated Cardiomyopathy
Dilated Cardiomyopathy (DCM) is a condition where the heart becomes enlarged and weakened, often due to genetic mutations, leading to reduced heart function and symptoms like shortness of breath and fatigue.
Dilated Cardiomyopathy: Candesartan vs Placebo
We are studying whether early treatment with candesartan can help prevent heart function decline in people with a genetic risk for dilated cardiomyopathy who currently have no symptoms. The trial also looks at the safety of this medication.
>2 years11-15 visitsConfirmation phase (III)Partially RemoteStandard MedicinesOralCardiologyInternal Medicine
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you between 18 and 64 years old?
- Do you have a history of heart problems, such as heart failure or a low heart function (LVEF ≤ 50%)?
- Are you currently pregnant or breastfeeding?
- Are you taking medications for high blood pressure, such as Lisinopril, Losartan, or Valsartan?
- Have you had any major health issues that could affect your ability to participate in a study, like severe kidney or liver disease?
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Altensil
Altensil
Amcandin
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Amsterdam UMC
Cardiology
Amstelveen, Netherlands
Academisch Ziekenhuis Maastricht
Cardiology
Maastricht, Netherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Cardiology
Rotterdam, Netherlands
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.