Dupilumab for Young Children with Uncontrolled Asthma

We are studying whether dupilumab can help reduce severe asthma attacks in children aged 2 to under 6 years. The trial will also evaluate the safety and tolerability of this treatment.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Beclomet
Beclomet is a medicine that helps prevent asthma symptoms by reducing inflammation in the airways.
Budesonide
Budesonide is a medicine that reduces swelling in the lungs and airways to help people with asthma and other breathing problems.
Dupixent
Dupixent is a medicine used to treat eczema and certain asthma symptoms.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Beclometasone Dipropionate
Beclometasone dipropionate is a corticosteroid substance that reduces airway inflammation to help prevent asthma symptoms.
Beclometasone Propionate
Beclometasone propionate is a corticosteroid substance that reduces inflammation in the airways or nasal passages to help control asthma and allergies.
Budesonide
Budesonide is a steroid substance that reduces inflammation in the airways to help control asthma and other respiratory conditions.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Abriff
Acorspray
Actamone

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Prvni plicni ambulance s.r.o.
Čakovice, Czechia
Centre Hospitalier Intercommunal Creteil
Service de Pediatrie
Créteil, France
Robert Debre University Hospital
Pneumologie, Allergologie, CRCM Pediatrique
Le Pré-Saint-Gervais, France

Sponsor: Sanofi-Aventis Research & Development
Last updated: Nov 26, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.