Dupuytren Contracture: Needle Procedure with Corticosteroid Injection

We are comparing a needle procedure with a corticosteroid injection to one with a saline injection for Dupuytren Contracture in the hand. This study aims to see if the corticosteroid helps reduce the chance of the condition returning.

>2 years≤5 visitsConfirmation phase (III)Standard MedicinesInjectionDermatologyOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Depo Medrol
Depo Medrol is an injectable medicine that reduces inflammation and eases pain from arthritis, joint swelling, and some allergic conditions.
Saline
Saline is a sterile saltwater solution used to hydrate patients, replace lost fluids, and rinse wounds or medical equipment.
Xylocaine 10%
Xylocaine 10% is a topical numbing medicine used to temporarily numb skin or mucous membranes before medical procedures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anhydrous Lidocaine Hydrochloride
Anhydrous Lidocaine Hydrochloride is a local anesthetic substance used to numb skin and tissues for minor procedures or relieve localized pain.
Lidocaine
Lidocaine is a substance that numbs skin and tissues to reduce pain during minor procedures or injections.
Methylprednisolone Acetate
Methylprednisolone acetate is a corticosteroid substance used to reduce inflammation and suppress immune responses.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Actilogic
Acuolens
Addex Natriumklorid

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Regionshospitalet Horsens
Department of Orthopedic Surgery
Horsens, Denmark
Regionshospitalet Randers
Department of Orthopedic Surgery
Randers, Denmark
Silkeborg Regional Hospital
Elective Surgery Centre
Silkeborg, Denmark
Sponsor: Regionshospitalet Horsens
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.