Dupuytren's Contracture
Dupuytren's contracture is a hand condition where the fingers bend towards the palm due to thickening of the tissue under the skin, leading to difficulty in straightening the fingers.
Dupuytren's Contracture: Bacterial Collagenase Treatment
We are studying a new bacterial collagenase injection for patients with Dupuytren's contracture to see if it improves hand function and reduces contracture compared to a placebo.
6-12 months11-15 visitsSafety phase (I)Efficacy phase (II)Investigational MedicinesInjectionOrthopedics and TraumatologyRheumatology
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have Dupuytren contracture (a hand condition causing fingers to bend) with a fixed flexion of at least 20°?
- Are you currently pregnant or breastfeeding?
- Are you taking any blood thinners or anticoagulants like Warfarin, Eliquis, or Xarelto?
- Have you had any treatments for Dupuytren contracture before this study?
What experimental substances are being tested?
Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.
Vibrio Alginolyticus Collagenase
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Medical University Of Graz
Klinische Abteilung für Plastische, Ästhetische und Rekonstruktive Chirurgie
Graz, Austria
Noe LGA Gesundheit Region Mitte GmbH
Klinische Abteilung für Plastische, Ästhetische und Rekonstruktive Chirurgie
Sankt Pölten, Austria
Helios Klinikum Bonn/Rhein-Sieg
Klinik für Hand- und Plastische Chirurgie
Alfter, Germany
Sponsor: Fidia Farmaceutici S.p.A.
Last updated: Nov 26, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.