Dupuytren's Contracture: Comparing Treatment Options

We are studying three different treatments for Dupuytren's contracture to see which one works best and is most cost-effective. This trial includes patients with mild to moderate cases and will track outcomes over several years.

>2 years Confirmation phase (III)No Placebo Standard Medicines InjectionDermatologyOrthopedics and Traumatology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Collagenase Clostridium Histolyticum

Collagenase Clostridium Histolyticum is a substance that breaks down excess collagen to help loosen tissue cords causing Dupuytren's contracture and Peyronie's disease.

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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HUS-Yhtymae

Department of Hand Surgery

Helsinki, Finland

Central Finland Hospital District Central Finland Hospital Nova

Department of Hand Surgery

Jyväskylä, Finland

Kuopio University Hospital

Department of Hand Surgery

Kuopio, Finland

Sponsor: Pirkanmaan hyvinvointialue

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.