Febrile Urinary Tract Infection
A febrile urinary tract infection (fUTI) is a type of urinary tract infection that causes fever and other symptoms, indicating that the infection may have spread to the kidneys or bloodstream.
E. coli Urinary Tract Infection: Pivmecillinam Treatment
We are studying whether an oral medication called pivmecillinam is as effective as standard treatments for E. coli urinary tract infections. This trial will also assess safety and other health effects.
What diseases are being studied?
Health conditions and diseases that the clinical trial is designed to study and treat.
Who can participate in the clinical trial?
These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..
- Are you at least 18 years old?
- Do you have a urinary tract infection (UTI) with symptoms like fever, flank pain, or painful urination?
- Have you been treated with antibiotics for your UTI for 2 days or more?
- Are you currently pregnant or breastfeeding?
- Do you have severe kidney problems or a kidney transplant?
What medicines are being studied?
Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.
Amikacin
Azactam
Azactam is an antibiotic used to treat serious bacterial infections, including some urinary, lung, and bloodstream infections.
Cefotax
Cefotax is an antibiotic medicine used to treat serious bacterial infections such as pneumonia, bloodstream infections, and meningitis.
Ceftriaxone
Ceftriaxone is an antibiotic used to treat serious bacterial infections such as pneumonia, meningitis, and severe bloodstream infections.
Cefuroxime
Cefuroxime is an antibiotic medicine used to treat common bacterial infections of the lungs, sinuses, skin, and urinary tract.
Ertapenem
Ertapenem is an antibiotic medicine used to treat a range of moderate to serious bacterial infections.
Meropenem
Meropenem is a strong antibiotic used to treat serious bacterial infections, often in hospital settings.
Pivmecillinam Hydrochloride Milpharm
Pivmecillinam Hydrochloride Milpharm is an antibiotic medicine used to treat urinary tract infections.
What active substances are being studied?
Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.
Amikacin
Amikacin is an antibiotic substance used to treat serious bacterial infections, especially those caused by gram-negative bacteria.
Amikacin Sulfate
Amikacin sulfate is an antibiotic substance used to treat serious bacterial infections, particularly severe Gram-negative infections.
Amoxicillin
Amoxicillin is an antibiotic substance used to treat a range of common bacterial infections such as ear, throat, and urinary tract infections.
Amoxicillin Sodium
Amoxicillin Sodium is an antibiotic substance used to treat common bacterial infections.
Ampicillin
Ampicillin is an antibiotic substance used to treat various bacterial infections.
Ampicillin Sodium
Ampicillin sodium is an antibiotic substance used to treat a range of bacterial infections.
Aztreonam
Aztreonam is an antibiotic substance used to treat infections caused by certain bacteria, especially Pseudomonas.
Betamethasone Valerate
Betamethasone valerate is a topical corticosteroid substance that reduces skin inflammation, itching, and redness from conditions like eczema and psoriasis.
Bromhexine Hydrochloride
Bromhexine hydrochloride is a substance that thins and loosens mucus in the airways to help clear coughs.
Cefotaxime
Cefotaxime is an antibiotic substance used to treat serious bacterial infections by stopping bacteria from growing.
Ceftriaxone
Ceftriaxone is an antibiotic substance used to treat serious bacterial infections and is usually given by injection.
Ceftriaxone Sodium
Ceftriaxone sodium is an antibiotic substance used to treat many serious bacterial infections, including pneumonia, bloodstream infections, and meningitis.
Cefuroxime
Cefuroxime is an antibiotic substance used to treat common bacterial infections like those of the respiratory tract, urinary tract, and skin.
Cefuroxime Axetil
Cefuroxime axetil is an antibiotic substance used to treat a range of bacterial infections, including respiratory, skin, and urinary tract infections.
Cefuroxime Sodium
Cefuroxime sodium is an antibiotic substance used to treat bacterial infections such as respiratory, urinary tract, and skin infections.
Cilastatin Sodium
Cilastatin sodium is a substance that prevents kidney breakdown of certain antibiotics, protecting the kidneys and prolonging the antibiotics' effectiveness.
Ciprofloxacin
Ciprofloxacin is an antibiotic used to treat various bacterial infections, such as urinary, respiratory, and skin infections.
Ciprofloxacin Hydrochloride
Ciprofloxacin hydrochloride is an antibiotic substance used to treat a variety of bacterial infections.
Clavulanic Acid
Clavulanic acid is a substance that helps certain antibiotics work against bacteria that would otherwise resist them.
Ertapenem
Ertapenem is an antibiotic substance used to treat serious bacterial infections.
Ertapenem Sodium
Ertapenem sodium is an antibiotic substance used to treat serious or complicated bacterial infections, typically given by injection.
Fosfomycin
Fosfomycin is an antibiotic substance used to treat bacterial infections, commonly prescribed for uncomplicated urinary tract infections.
Fosfomycin Calcium
Fosfomycin calcium is an antibiotic substance used to treat bacterial infections, especially urinary tract infections.
Gentamicin
Gentamicin is an antibiotic used to treat serious bacterial infections, especially those caused by gram-negative bacteria.
Gentamicin Sulfate
Gentamicin sulfate is an antibiotic used to treat serious bacterial infections, especially those caused by gram-negative bacteria.
Imipenem
Imipenem is an antibiotic substance used to treat serious bacterial infections by killing or stopping the growth of bacteria.
Lidocaine
Lidocaine is a substance that numbs skin and tissues to reduce pain during minor procedures or injections.
Lidocaine Hydrochloride
Lidocaine hydrochloride is a substance that numbs a specific area to relieve pain during minor procedures and dental treatments.
Linezolid
Linezolid is an antibiotic substance used to treat serious Gram-positive bacterial infections, including resistant strains.
Meropenem
Meropenem is an antibiotic substance used to treat serious bacterial infections, including severe or hospital-acquired infections.
Meropenem Anhydrous
Meropenem anhydrous is an antibiotic substance used to treat severe bacterial infections by killing a wide range of bacteria.
Meropenem Trihydrate
Meropenem trihydrate is an antibiotic substance used to treat serious bacterial infections.
Piperacillin
Piperacillin is an antibiotic substance used to treat serious bacterial infections, including those caused by Pseudomonas and other gram-negative bacteria.
Piperacillin Sodium
Piperacillin sodium is an antibiotic substance used to treat serious bacterial infections, including those caused by Pseudomonas.
Pivmecillinam
Pivmecillinam is an antibiotic substance used to treat urinary tract infections caused by common bacteria.
Pivmecillinam Hydrochloride
Pivmecillinam hydrochloride is an antibiotic substance used to treat urinary tract infections.
Sulfamethoxazole
Sulfamethoxazole is an antibiotic substance used to treat a range of bacterial infections, including urinary and respiratory tract infections.
Tazobactam Sodium
Tazobactam sodium blocks bacterial enzymes that inactivate antibiotics, helping them treat infections caused by resistant bacteria.
Tobramycin
Tobramycin is an antibiotic substance used to treat serious bacterial infections, especially those affecting the lungs and eyes.
Trimethoprim
Trimethoprim is an antibiotic that treats bacterial infections, commonly used for urinary tract infections.
What similar medicines might you know?
Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.
Agenor
Agenorem
Amicacina
Amicacina Hikma
Amicacina Kabi
Amikacin Fresenius
Amikacin Hameln Pharma
Amikacin Olikla
Amikacina Kabi
Amikacina Teva
Amikacine Fresenius Kabi
Amikacine Hospira
Amikacine Kabi
Anaptivan
Antadar I.M.
Antadar I.V.
Antibioxime
Aprok
Aprokam
Archifar
Axetine
Beloxim
Betasporina
Betasporina Im
Betasporina Iv
Biofuroksym
Bioracef
Biorisan
Biotaksym
Biotrakson
Bixon
Bresec
Bresec(Iv)
Brucelin
Carbenem
Caritex
Cayston
Ceferoxan
Cefort
Cefotaksim Mip
Cefotaxim Eberth
Cefotaxim Mip
Cefotaxim Mip Pharma
Cefotaxim Navamedic
Cefotaxim Swyssi
Cefotaxim-Saar Mip Pharma
Cefotaxim-Saar Mip Pharma Gmbh
Cefotaxima Atb
Cefotaxima Eg
Cefotaxima Sala
Cefotaxima Torlan
Cefotaxime Mip
Cefotaxime Mip Pharma
Cefotaxime Noridem
Cefotaxime Noridem Enterprises
Cefotaxime Panpharma
Cefotaxime Reig Jofre Uk
Cefotaxime Sandoz Ltd
Cefotaxime Sodium
Cefotaxime Swyssi
Cefotaxime Viatris
Cefotrix
Cefox
Cefrag
Cefriaxona Asklepius Sidefarma
Ceftal
Ceftazidim Swyssi
Ceftriakson Aptapharma
Ceftriakson Kalceks
Ceftriakson Pontus
Ceftriakson Qilu
Ceftriakson Swyssi
Ceftriaxon "kalceks"
Ceftriaxon Aptapharma
Ceftriaxon Bradex
Ceftriaxon Cnp
Ceftriaxon Dali Pharma
Ceftriaxon Eberth
Ceftriaxon Fresenius Kabi
Ceftriaxon Hexal
Ceftriaxon Hikma
Ceftriaxon Kabi
Ceftriaxon Medochemie
Ceftriaxon Mip
Ceftriaxon Mip Pharma
Ceftriaxon Navamedic
Ceftriaxon Panpharma
Ceftriaxon Pharmacenter
Ceftriaxon Puren
Ceftriaxon Qilu
Ceftriaxon Ratiopharm
Ceftriaxon Saar
Ceftriaxon Swyssi
Ceftriaxon-Dinatrium · 3,5 H2o Saar
Ceftriaxon-I.V. Mip
Ceftriaxon-I.V./I.M. Mip
Ceftriaxonă Aptapharma
Ceftriaxona Asklepius
Ceftriaxona Bradex
Ceftriaxona Fresenius
Ceftriaxona Fresenius Kabi
Ceftriaxona Hikma
Ceftriaxona I.V. Generis
Ceftriaxona Im Hikma
Ceftriaxona Iv Hikma
Ceftriaxona Kabi
Ceftriaxona Kalceks
Ceftriaxona Labesfal
Ceftriaxona Labesfal Farma
Ceftriaxona Ldp Torlan
Ceftriaxona Medlink Im
Ceftriaxonă Mip
Ceftriaxona Omnicals
Ceftriaxona Qilu
Ceftriaxona Sala
Ceftriaxona Sandoz
Ceftriaxonă Swyssi
Ceftriaxone Accord
Ceftriaxone Aft Pharma Uk
Ceftriaxone Almus
Ceftriaxone Alter
Ceftriaxone Arrow
Ceftriaxone Aurobindo
Ceftriaxone Bcpp
Ceftriaxone Biogaran
Ceftriaxone Biopharma
Ceftriaxone Cox Pharmaceutical
Ceftriaxone Cristers
Ceftriaxone Dali Pharma
Ceftriaxone Doc Generici
Ceftriaxone Evolugen
Ceftriaxone Fresenius Kabi
Ceftriaxone Git
Ceftriaxone Istituto Biochimico Italiano G. Lorenzini
Ceftriaxone Jed Pharma
Ceftriaxone Kabi
Ceftriaxone Kalceks
Ceftriaxone Medlink
Ceftriaxone Mip
Ceftriaxone Mip Pharma
Ceftriaxone Mylan Generics
Ceftriaxone Noridem Emterpirses
Ceftriaxone Noridem Enterprises
Ceftriaxone Norma
Ceftriaxone Northumbria Pharma
Ceftriaxone P-Care
Ceftriaxone Panpharma
Ceftriaxone Pensa
Ceftriaxone Pharmsol
Ceftriaxone Piam Farmaceutici
Ceftriaxone Pinewood Laboratories
Ceftriaxone Qilu
Ceftriaxone Qilu Pharma Spain
Ceftriaxone Ratiopharm
Ceftriaxone Reig Jofre Uk
Ceftriaxone Sandoz Ltd
Ceftriaxone Sapiens
Ceftriaxone Swyssi
Ceftriaxone Swyssi 1 G
Ceftriaxone Swyssi 2 G
Ceftriaxone Tamrisa
Ceftriaxone Tecnigen
Ceftriaxone Teva Sante
Ceftriaxone Tzf
Ceftriaxone Unifarma
Ceftriaxone Viatris
Ceftriaxone Vyocure
Ceftriaxone Vyocure Ab
Ceftriaxone Wockhardt Uk
Ceftriaxone Zentiva
Ceftriaxone Zydus
Ceftron
Cefur
Cefurax
Cefuroksim Aptapharma
Cefuroprol
Cefurox
Cefuroxim 1 A Pharma
Cefuroxim Al
Cefuroxim Aptapharma
Cefuroxim Aristo
Cefuroxim Ascend
Cefuroxim Astro
Cefuroxim B. Braun
Cefuroxim Cnp
Cefuroxim Dr. Eberth
Cefuroxim Fresenius
Cefuroxim Fresenius Kabi
Cefuroxim Heumann
Cefuroxim Hikma
Cefuroxim Kabi
Cefuroxim Kalceks
Cefuroxim Krka
Cefuroxim Mip
Cefuroxim Mip Pharma
Cefuroxim Mylan
Cefuroxim Navamedic
Cefuroxim Qilu
Cefuroxim Saar
Cefuroxim Sandoz
Cefuroxim Stada
Cefuroxim Sun
Cefuroxim Zur Infusion Fresenius
Cefuroxima
Cefuroxima Alter
Cefuroxima Aristo
Cefuroxima Atb
Cefuroxima Baroque Healthcare, Lda.
Cefuroxima Basi
Cefuroxima Cinfa
Cefuroxima Codramol
Cefuroxima Eg
Cefuroxima Eg Spa
Cefuroxima Fresenius Kabi
Cefuroxima Hikma
Cefuroxima Im Hikma
Cefuroxima Iv Hikma
Cefuroxima K24 Pharmaceuticals
Cefuroxima Kern Pharma
Cefuroxima Krka
Cefuroxima Labesfal
Cefuroxima Maxmind
Cefuroximă Mip
Cefuroxima Mylan
Cefuroxima Normon
Cefuroxima Pensa
Cefuroxima Reig Jofre
Cefuroxima Sala
Cefuroxima Stada
Cefuroxima Sun
Cefuroxima Tecnigen
Cefuroxima Teva-Ratio
Cefuroximaxetil Sandoz B.V.
Cefuroxime Aft Pharma Uk
Cefuroxime Aptapharma
Cefuroxime Aristo
Cefuroxime Arrow
Cefuroxime Bcpp
Cefuroxime Consilient Health
Cefuroxime Cristers
Cefuroxime Dali Pharma
Cefuroxime Dr. Eberth
Cefuroxime Eg
Cefuroxime Fresenius Kabi
Cefuroxime Generics [uk]
Cefuroxime Genoptim
Cefuroxime Istituto Biochimico Italiano G. Lorenzini
Cefuroxime Kabi
Cefuroxime Kalceks
Cefuroxime Krka
Cefuroxime Mip
Cefuroxime Mip Pharma
Cefuroxime Orion Pharma
Cefuroxime Panpharma
Cefuroxime Reig Jofre Uk
Cefuroxime Sandoz
Cefuroxime Sandoz Ltd
Cefuroxime Synto
Cefuroxime Teva
Cefuroxime Tzf
Cefuroxime Viatris
Cefuroximnatrium Sandoz
Ceroxim
Chemacin
Ciplacef
Claxon
Curocef
Curoxim
Davixon
Daytrix
Diaxone
Efox
Eftry
Emblaveo
Eraxitron
Ertapenem "aptapharma"
Ertapenem Acs Dobfar
Ertapenem Added Pharma
Ertapenem Anfarm
Ertapenem Arrow
Ertapenem Aspire Pharma
Ertapenem Atb
Ertapenem Aurobindo
Ertapenem Aurovitas
Ertapenem Elc
Ertapenem Eugia
Ertapenem Generis
Ertapenem Hikma
Ertapenem Hikma Farmacêutica (Portugal)
Ertapenem Medlink
Ertapenem Milpharm
Ertapenem Panmedica
Ertapenem Panpharma
Ertapenem Qilu
Ertapenem Steriscience
Ertapenem Sun
Ertapenum Cipla
Farcef
Fidato
Flexelite
Fotaxil
Fredyr
Furexa
Furextil
Furocef
Glorixone
Gonif
Homepen
Iceca
Infeflox
Interbion
Invanz
Itorex
Kemudin
Kemudin I.M.
Kemudin I.V.
Kocefan
Lanomycin
Lendacin
Letynol I.V
Loditer
Longaceph
Lopratin
Lukadin
Medaxone
Medaxone Plusolv
Medaxonum
Medopenem
Medoxem
Medoxin
Mepenex
Meperya
Merobact
Merocarb
Meronem
Meronem I.V.
Meronem Iv
Meropenem "thrive"
Meropenem Accordpharma
Meropenem Acs Dobfar
Meropenem Anfarm
Meropenem Antibiotice
Meropenem Arrow
Meropenem Arrow Lab
Meropenem Atral
Meropenem Aurobindo
Meropenem Aurovit
Meropenem B. Braun Melsungen
Meropenem Bausch Health
Meropenem Bradex
Meropenem Cf
Meropenem Color
Meropenem Dr. F. Eberth
Meropenem Enexi
Meropenem Farmalider
Meropenem Fresenius Kabi
Meropenem Generis Phar
Meropenem Hikma
Meropenem Hikma Farmacêutica (Portugal)
Meropenem Kabi
Meropenem Kern Pharma
Meropenem Ldp Torlan
Meropenem Ldp-Laboratorios Torlan
Meropenem Ligula Pharma
Meropenem Medlink
Meropenem Navamedic
Meropenem Noridem
Meropenem Noridem Enterprises
Meropenem Pharmacenter
Meropenem Qilu
Meropenem Ranbaxy (Uk)
Meropenem Stada
Meropenem Steriscience
Meropenem Sun
Meropenem Venus
Meropenem Venus Pharma
Meropenem Wh
Meropenil
Meroponia
Merosap
Merovan Iv
Merozan
Merrem
Monacef
Moxicef
Nekacin
Nilson
Nipogalin
Normafenac
Olicef
Oraxim
Osaera
Oximezin
Panatrix
Pantoxon
Penemer
Penemnia
Penomax
Pivinorm
Pivmecilinam Aurobindo
Pivmecillinam Hydrochloride Karo Pharma
Pivmecillinamhydrochlorid Karo Pharma
Pivmelam
Prokam
Ragex
Refoxim
Resibelacta
Resibelacta Iv
Rexorem
Rezaxon
Ricefan
Rocephine Iv
Rocephine Iv Iv
Rolisporin 1g/Vial
Rolisporin 2g/Vial
Ronepem
Rovericlin
Santamer
Seftrion
Selexid
Setriox
Suknam
Syntoxime
Tarcefoksym
Tarsime
Tartriakson
Taximed
Travilan
Triacefan
Valexime
Valoran
Veracol
X-Systo
Ximaract
Xorimax
Xsysto
Xylanal
Yokel
Zanetin
Zilisten
Zinacef
Zinnat
Zinoxx
Zipos
Znobact
Zofiren
Zoref
Zyntax
Аксетин
Аксеф
Ертапенем Аптафарма
Зинат
Лифурокс
Медаксон
Мепенекс
Меропе
Меропенем Енекси
Неофуроксим
Фурекстил
Фуроцеф
Цероксим
Цефамед
Цефотаксим Mip
Цефтриаксон Mip
Цефтриаксон Аптафарма
Цефтриаксон Панфарма
Цефтриаксон Тенамид
Цефтриаксон Чайкафарма
Цефурокон
Цефуроксим Mip
Цефуроксим Неклайф
Цефуроксим Тенамид
Where is the clinical trial being conducted?
Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.
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Helse Bergen HF
Dept. of Infectious Diseases
Bergen, Norway
Oslo University Hospital HF
Dept. of Infectious Diseases
Oslo, Norway
Soedra Aelvsborg Hospital Vaestra Goetalandsregionen
Infektionskliniken
Borås, Sweden
Malarsjukhuset Eskilstuna
Infektionskliniken
Eskilstuna, Sweden
Region Blekinge
Blekingesjukhuset, Infektionskliniken
Karlskrona, Sweden
Region Skane Skanes Universitetssjukhus
Infektionsklinken
Lund, Sweden
Region Oerebro Laen
Universitetssjukhuset Örebro, VO Infektion
Örebro, Sweden
Sahlgrenska University Hospital-Vaestra Goetalandsregionen
Verksamhet Infektion
Partille, Sweden
Karolinska University Hospital
Medicinska Enheten för infektionssjukdomar
Solna, Sweden
Region Vaesternorrland
Länssjukhuset Sundsvall-Härnösand, Infektionskliniken
Sundsvall, Sweden
Region Vaesterbotten
Norrlands Universitetssjukhus, Infektionskliniken
Umeå, Sweden
Uppsala University Hospital
Infektionskliniken
Uppsala, Sweden
Region Kronoberg
Centrallasarettet Växjö, Infektionskliniken
Växjö, Sweden
Sponsor: Uppsala Universitet
Last updated: Nov 27, 2025
Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.