Early Alzheimer's Disease: Sabirnetug Infusions

We are studying whether intravenous sabirnetug can slow cognitive decline in people with early Alzheimer's disease compared to a placebo. This trial aims to find new ways to help manage symptoms and improve quality of life.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Amyvid
Amyvid is an imaging agent used in PET scans to help detect amyloid plaques in the brain when evaluating Alzheimer’s disease.
Neuraceq
Neuraceq is a PET imaging agent used to help detect brain changes linked to Alzheimer’s disease.
Sabril
Sabril is a medicine used to treat certain types of seizures in people with epilepsy, including infantile spasms and hard-to-control seizures.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Florbetaben (18f)
Florbetaben (18F) is a radioactive imaging tracer used in PET scans to show amyloid plaque buildup in the brain for Alzheimer's evaluation.
Florbetapir (18f)
Florbetapir (18F) is a radioactive tracer used in PET scans to detect abnormal protein deposits in the brain linked to Alzheimer's disease.
Flutemetamol (18f)
Flutemetamol (18F) is a radioactive PET imaging agent used to detect amyloid plaques in the brain to help evaluate Alzheimer’s disease.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Acu193

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Kigabeq
Sabril Beutel
Sabril Filmomhulde Tablet

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Centre Hospitalier Universitaire De Bordeaux
Centre Mémoire de Ressources et de Recherche (CMRR)
Bordeaux, France
Hospices Civils De Lyon
Unité 502
Bron, France
Centre Hospitalier Universitaire Amiens Picardie
CMRR - Service de Neurologie
Colomiers, France

Sponsor: Acumen Pharmaceuticals Inc.
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.