Early Breast Cancer: Camizestrant vs. Standard Therapy

We are studying whether the new medication camizestrant can better prevent breast cancer recurrence in patients who have completed initial treatment. This trial involves individuals with ER+/HER2- early breast cancer at risk of returning after standard therapy.

>2 years6-10 visitsConfirmation phase (III)No PlaceboCost ReimbursementPartially RemoteInvestigational MedicinesOralInjectionOncology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Arimidex
Arimidex is a medicine used to treat certain types of breast cancer in postmenopausal women by lowering estrogen.
Exemestane
Exemestane is a medicine used to lower estrogen and treat certain breast cancers in women who have gone through menopause.
Goserelin Endomedica
Goserelin Endomedica is a medicine that lowers sex hormone levels to treat prostate cancer and some women's reproductive conditions like endometriosis.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Anastrozole
Anastrozole is a substance that lowers estrogen levels to help treat and prevent hormone-sensitive breast cancer in postmenopausal women.
Exemestane
Exemestane is a substance that lowers estrogen levels to help treat hormone-sensitive breast cancer in postmenopausal women.
Goserelin
Goserelin is a substance that lowers sex hormone levels to treat hormone-sensitive cancers and conditions.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Camizestrant

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Adifen 10mg
Adiunastrol
Agerdex

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Oberoesterreichische Gesundheitsholding GmbH
Innere Med.
Attnang-Puchheim, Austria
Medical University Of Graz
Klin. Abt. f. Onkologie
Graz, Austria
Medical University Of Graz
Klinische Abteilung fur Gynakologie
Graz, Austria
Sponsor: Astrazeneca AB
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.