Eosinophilic Asthma: Benralizumab Treatment Study

We are studying how well benralizumab works and its safety for people with eosinophilic asthma who are not well-controlled on standard treatments. This trial compares it to increasing their current medication dose.

1-2 years 6-10 visits Confirmation phase (III)Cost Reimbursement Partially Remote Standard Medicines Oral InjectionAllergologyPulmonology

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Fasenra

Fasenra is a medicine used to treat severe asthma that involves high levels of certain white blood cells.

Symbicort Forte Turbuhaler

Symbicort Forte Turbuhaler is an inhaler medicine used to prevent and control asthma and chronic obstructive lung disease symptoms.

Symbicort Turbuhaler

Symbicort Turbuhaler is an inhaler used to prevent and control asthma and chronic lung disease (COPD).

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Benralizumab

Benralizumab is a substance that reduces eosinophil immune cells to help control severe eosinophilic asthma.

Budesonide

Budesonide is a steroid substance that reduces inflammation in the airways to help control asthma and other respiratory conditions.

Formoterol Fumarate Dihydrate

Formoterol fumarate dihydrate is a substance that relaxes airway muscles to open breathing passages for people with asthma or COPD.

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

Acorspray

Aeromax

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Medical Center FAMA Medical Ltd.

Plovdiv, Bulgaria

Prevencia 2000 MCDMP

Plovdiv, Bulgaria

Specialized Hospital For Active Treatment Of Pneumo-Phthisiatric Diseases Dr. Dimitar Gramatikov-Ruse

Department of Pulmonology

Ruse, Bulgaria

Sponsor: AstraZeneca AB

Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.