Epidermolysis Bullosa: ABCB5+ Stem Cell Treatment

We are studying a new stem cell therapy for individuals with recessive dystrophic epidermolysis bullosa. The trial aims to see if this treatment is safe and effective compared to a placebo.

What diseases are being studied?

Health conditions and diseases that the clinical trial is designed to study and treat.

Who can participate in the clinical trial?

These questions help us understand your situation so we can let the trial team know whether you might be a potential match. This is not a medical evaluation and is not part of the official screening, the study doctor will make the final decision..

What medicines are being studied?

Medicines that are officially approved for use in the European Union and considered safe by EMA. These medicines are already on the market and may be tested for new conditions or populations.

Dibondrin
Efcortesol
Fexofenadine Hydrochloride 120mg Film-Coated Tablets
This medicine relieves allergy symptoms such as sneezing, itchy or watery eyes, and runny nose.

What active substances are being studied?

Active substances that are officially approved for use in the European Union and considered safe by EMA. These substances are already on the market and may be tested for new conditions or populations.

Cetirizine Dihydrochloride
Cetirizine Dihydrochloride is an antihistamine that relieves allergic symptoms like sneezing, runny nose, itchy eyes, and hives.
Chloropyramine Hydrochloride
Chloropyramine hydrochloride is a substance that blocks histamine to relieve allergic symptoms such as itching, hives, and a runny nose.
Chlorphenamine Maleate
Chlorphenamine maleate is a substance that relieves common allergy symptoms such as sneezing, runny nose, and itchy eyes.

What experimental substances are being tested?

Experimental substances that are being investigated in this clinical trial. These are not yet approved for general use.

Allo-Apz2-Ots
Cetirizine
Allogeneic Skin-Derived Abcb5-Positive Dermal Mesenchymal Stromal Cells

What similar medicines might you know?

Don't worry if you don't know the medicines tested in the trial. There is a chance you have heard about the similar medicines. Check the list below to see if you are familiar with any of them.

1 Year Plus Allergy Relief Antihistamine
A L E R I D
Aceterin

Where is the clinical trial being conducted?

Locations and medical facilities where this clinical trial is currently recruiting or conducting research. Select the locations where you would like to participate.

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Eb-Haus Austria Gemeinnuetzige Salzburger Landeskliniken Betriebsgesellschaft mbH
EB-Haus Austria, Universitätsklinik für Dermatologie und Allergologie
Salzburg, Austria
University Hospital Centre Zagreb
dermatovenerology
Zagreb, Croatia
Rigshospitalet
Center for rare diseases
Copenhagen, Denmark

Sponsor: Rheacell GmbH & Co. KG
Last updated: Nov 27, 2025

Disclaimer: Parts of this content have been automatically extracted from the EU Clinical Trials registry. While we strive for accuracy, please always contact the trial site or sponsor directly for correct and official information before making any decisions about participation. View on EU Clinical Trials.